Development of butyl rubber stopper mould in China

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Discussion on the development of domestic medical butyl rubber stopper mold

Medical butyl rubber stopper dispatched more than 23000 personnel 4. Sensor: the sensor is the main component of the accuracy and force invariance of the experimental machine. At present, the types of electronic universal experimental machine sensors on the market include S-type and spoke type. It has not been long since they were used and developed in China. Before 1983, natural rubber stopper was used in medical packaging in China, while Japan The United States and other developed countries realized the butyl gelatinization of pharmaceutical rubber plugs in the 1960s and 1970s. The main reasons for this replacement are: butyl rubber stopper can better meet the requirements of drug packaging than natural rubber in many properties; Practice shows that the air tightness of butyl rubber plug is 20 times that of natural rubber plug; Butyl rubber stopper has good waterproof performance and can effectively prevent mildew or failure of drugs due to the existence of water; The butyl rubber stopper has good stability and little corrosiveness to the packaged drugs. As natural rubber plugs have many problems, such as affecting drug quality and causing hidden dangers to human health, all developed countries have long eliminated natural rubber plugs and widely used butyl rubber plugs. Especially in recent years, the export of China's pharmaceutical products has been rejected by other countries because the packaging can not meet the requirements. In 1979, China began to develop butyl rubber stopper, which was successfully developed and passed the appraisal in 1983

the development of butyl rubber stopper mould in China began around 1985. At that time, Hubei Huaqiang introduced a full set of butyl rubber stopper production line from Italy, including forming mould. At the time of introduction, a set of ordinary antibiotic vulcanization mold was worth $80000. With the full production of Huaqiang butyl rubber stopper and the renewal of molds, the reality of expensive imported molds has gradually affected the normal production. At this time, some manufacturers represented by the state-owned Honglin machinery factory began to develop and trial produce butyl rubber plug molds. The difficulties in the production of butyl rubber plug mould are: high dimensional accuracy and consistency requirements, and high service life of the mould under high temperature and high pressure during vulcanization. As butyl rubber plug mold is a new industry, there is no existing data and experience in China to learn from. Honglin factory can only gradually explore the selection of materials and the exploration of processing technology. By 1990, Honglin factory completed the small batch production of antibiotic mold core and went to the butyl rubber plug factory for trial production. The results of trial production showed that it could completely replace the imported mold core. Moreover, due to the special vacuum quenching process, the hardness of the mold core reaches HRC, which improves the use of the mold core and promotes the transformation and upgrading of high-tech manufacturing industry. Practice has proved that the service life of machined vacuum quenching die core is twice that of imported die core. It is times the service life of domestic cold extrusion die core. But its price is only 1/10 of that of imported molds. By 1991, the molds produced by Honglin factory completely replaced the imported molds. In 1990, the domestic butyl rubber plug industry began to produce freeze-dried rubber plugs, and its molds are all imported, and the price is more expensive. A set of vulcanization mold is up to 200000 US dollars. Due to the complex shape of freeze-dried mold core and the use of EDM abroad, the processing cycle is particularly long and the cost is expensive. Due to the limitations of equipment and technology, mass production cannot be formed in China. Honglin mould factory, in combination with the actual situation in China, has opened another Xi path to explore the production of freeze-dried mould core with inlaid structure. After two years of exploration, it has overcome the persistent problem of glue leakage of inlaid freeze-dried mould core, so that the production qualified rate reaches 95%, and its price is only one fifteenth of that of imported mould core. The freeze-dried mold core produced by Honglin mold has been widely used by Jiangyin Lanling and Hubei Huaqiang, the main manufacturers of freeze-dried rubber plugs in China in just two years. In 2002, the freeze-dried core produced by Honglin mould accounted for 80% of the domestic market. It has greatly promoted the development of domestic butyl rubber plug industry

with the end of 2004, the National Pharmaceutical Packaging Association required to completely replace the natural rubber plug with butyl rubber plug. The rapid development of domestic butyl rubber stopper industry has also driven the rapid development of butyl rubber stopper mould. Now, domestic butyl rubber stopper mould has been completely localized. However, it should be clearly seen that China's butyl rubber plug molds are still in the development stage, the butyl rubber plug molds with complex shapes still need to be imported from abroad, and the domestic butyl rubber plug molds do not have their own industry standards, which is not only detrimental to the development of butyl rubber plug industry, but also restricts the development of butyl rubber plug mold industry. In the future work, butyl rubber plug production enterprises and mold production enterprises should communicate and contact with each other for common development, Work together for the development of rubber plug and rubber plug mold industry in China. (end)

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